Full AstraZeneca vaccine side effects as low risk blood clots added to list

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Blood clots have been added as an extremely rare side effect of the AstraZeneca vaccine.

On Wednesday, the UK’s medical regulator announced that under 30s would now be recommended an alternative vaccine to the Oxford AstraZeneca vaccine over concerns of blood clots.

By March 31, 2021, 20.2 million doses of the vaccine had been given in the UK, meaning the overall risk of these blood clots is approximately four people in a million who receive the vaccine.

According to Dr Gill Richardson, head of the vaccine rollout in Wales, signs of the severe reaction to the vaccine include a severe and acute headache that lasts more than four days after the vaccine has been delivered, as well as unusual bruising in the shot area, and possible nausea.

Dr Richardson told BBC Radio Wales on Thursday that this guidance has been issued to all health professionals and health boards in Wales following the Medicines and Healthcare products Regulatory Agency’s (MHRA) announcement on Wednesday.

While changes have been made to who should have the AstraZeneca vaccine, the MHRA stressed that the benefits of the vaccine outweigh the risks in older adults, who are far more likely to die of Covid.

The most common side effect people experience from the AstraZeneca vaccine includes developing a fever and it is common to develop a fever after many vaccinations, not just the Covid ones.

Other symptoms, which can be described as “flu-like symptoms” are common after receiving many vaccines, and this is the same for the Covid-19 approved vaccines.

Here is the full list of side effects of the Oxford AstraZeneca vaccine listed on the UK Government website:

Very common (may affect more than 1 in 10 people):

  • tenderness, pain, warmth, itching or bruising where the injection is given
  • generally feeling unwell
  • feeling tired (fatigue)
  • chills or feeling feverish
  • headache
  • feeling sick (nausea)
  • joint pain or muscle ache

Common (may affect up to 1 in 10 people):

  • swelling, redness or a lump at the injection site
  • fever
  • being sick (vomiting) or diarrhoea
  • flu-like symptoms, such as high temperature, sore throat, runny nose, cough and chills

Uncommon (may affect up to 1 in 100 people):

  • feeling dizzy
  • decreased appetite
  • abdominal pain
  • enlarged lymph nodes
  • excessive sweating, itchy skin or rash

Not known (cannot be estimated from the available data)

  • severe allergic reaction (anaphylaxis)
    According to the UK Government, in clinical trials there were very rare reports of events associated with inflammation of the nervous system, which may cause numbness, pins and needles and or loss of feeling. However, it is not confirmed whether these events were due to the vaccine.


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Some people who received the vaccine report a sudden feeling of cold with shivering/shaking accompanied by a rise in temperature, possibly with sweating, headache, nausea, muscle aches and feeling unwell, starting within a day of having the vaccine and usually lasting for a day or two.

People are being told that if their fever lasts longer than two or three days, or the symptoms persist, it may not be due to side effects of the vaccine and medical advice should be sought.

Those who experience any side effects which are not listed above are encouraged to get in touch with their doctor, pharmacist or nurse.

There is also a dedicated website, Coronavirus Yellow Card reporting site which is also available as an app to report side effects to.

Reporting side effects is important as it helps health professionals improve their understanding of the vaccine and its safety.



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